Jack Burton is a big-talking, wisecracking trucker who goes beneath the streets of San Francisco's Chinatown to battle an army of spirits when his friend's fiancee is kidnapped.

Daniel Hillard is no ordinary father, so when he learns his ex-wife needs a housekeeper, he applies for the job. With the perfect wig, a little makeup and a dress for all occasions, he becomes Mrs. Doubtfire, a devoted British housekeeper who is hired on the spot. Free to be the "woman" he never knew he could be, the disguised Daniel creates a whole new life with his entire family.